Product Overview
WR99210 | T17257 | TargetMol Chemicals
CAS: 47326-86-3
Smiles: CC1(C)N=C(N)N=C(N)N1OCCCOc1cc(Cl)c(Cl)cc1Cl
Formula: C14H18Cl3N5O2
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Metabolism|||Microbiology/Virology
Target: DHFR|||Antifolate|||Antibacterial
Receptor: N/A
Bioactivity: WR99210 is effective against the most pyrimethamine-resistant Plasmodium falciparum strains. WR99210 is an effective inhibitor of dihydrofolate reductase (IC50:<0.075 nM).
Molecular Weight: 394, 68