Product Overview
WZ4002-hydroxy | T35147 | TargetMol Chemicals
CAS: T35147
Smiles: C=CC(NC1=CC=CC(OC2=NC(NC3=CC=C(C=C3O)N4CCN(CC4)C)=NC=C2Cl)=C1)=O
Formula: C24H25ClN6O3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: WZ4002-hydroxyl is a WZ4002 derivative or WZ4002 analogue in which methoxy is replaced by hydroxyl and can be detected in 50% of patients with clinical resistance to gefitinib or erlotinib. WZ4002 has a basic chemical skeleton (covalent pyrimidine) that differs from other EGFR inhibitors.
Molecular Weight: 480, 95