Product Overview
WZ4003 | T6291 | TargetMol Chemicals
CAS: 1214265-58-3
Smiles: CCC(=O)Nc1cccc(Oc2nc(Nc3ccc(cc3OC)N3CCN(C)CC3)ncc2Cl)c1
Formula: C25H29ClN6O3
Pathway: PI3K/Akt/mTOR signaling
Target: AMPK
Receptor: N/A
Bioactivity: WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively. It is no significant inhibition on 139 other kinases.
Molecular Weight: 497
