XE 991 dihydrochloride | T17262

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TMC-T17262
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Product Overview

XE 991 dihydrochloride | T17262 | TargetMol Chemicals

CAS: 122955-13-9

Smiles: Cl.Cl.O=C1c2ccccc2C(Cc2ccncc2)(Cc2ccncc2)c2ccccc12

Formula: C26H22Cl2N2O

Pathway: Membrane transporter/Ion channel|||Others

Target: Others|||Potassium Channel

Receptor: N/A

Bioactivity: XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively).

Molecular Weight: 449, 38

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