Product Overview
Xevinapant hydrochloride | T3299 | TargetMol Chemicals
CAS: 1071992-57-8
Smiles: Cl.CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)CC(C)C
Formula: C32H44ClN5O4
Pathway: Apoptosis
Target: Apoptosis|||IAP
Receptor: N/A
Bioactivity: AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.
Molecular Weight: 598, 19
