Product Overview
XL228 | T17267 | TargetMol Chemicals
CAS: 898280-07-4
Smiles: CC(C)c1cc(CNc2nc(Nc3cc([nH]n3)C3CC3)cc(n2)N2CCN(C)CC2)on1
Formula: C22H31N9O
Pathway: Angiogenesis|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: IGF-1R|||Bcr-Abl|||Src|||Aurora Kinase
Receptor: N/A
Bioactivity: XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).
Molecular Weight: 437, 552
