Product Overview
Y06037 | T24404 | TargetMol Chemicals
CAS: T24404
Smiles: CC1=NOC2=CC=C(C3=NC4=CC=C(N5[C@@H](C)COCC5)C=C4N3CC6CCCCC6)C=C12
Formula: C27H32N4O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Y06037 is a BET inhibitor for the potential treatment of Castration-Resistant Prostate Cancer (CRPC). It potently inhibited cell growth, colony formation, and the expression of AR, AR-regulated genes and MYC in prostate cancer cell lines. Y06037 bounds to the BRD4(1) bromodomain (Kd: 81 nM).
Molecular Weight: 444, 58