Product Overview
YHO-13177 | T4595 | TargetMol Chemicals
CAS: 912287-56-0
Smiles: COc1ccc(cc1OC)C(=C\c1ccc(s1)N1CCC(O)CC1)\C#N
Formula: C20H22N2O3S
Pathway: Membrane transporter/Ion channel
Target: BCRP
Receptor: N/A
Bioactivity: YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel resistance in MDR1-transduced human leukemia K562 cells.
Molecular Weight: 370, 47
