Product Overview
YKL-05-099 | T17271 | TargetMol Chemicals
CAS: 1936529-65-5
Smiles: COc1ccc(nc1)N1C(=O)N(Cc2cnc(Nc3ccc(cc3OC)C3CCN(C)CC3)nc12)c1c(C)cccc1Cl
Formula: C32H34ClN7O3
Pathway: PI3K/Akt/mTOR signaling
Target: SIK
Receptor: N/A
Bioactivity: YKL-05-099 is an inhibitor of the salt-inducible kinase(SIK1 and SIK3 ; IC50s: 10 and 30 nM, respectively). It has a slightly less potent SIK2-inhibitory (IC50:40 nM).
Molecular Weight: 600, 12
