Product Overview
YM-430 | T29183 | TargetMol Chemicals
CAS: 153192-22-4
Smiles: COC(=O)C1=C(C)NC(C)=C([C@H]1c1cccc(c1)[N+]([O-])=O)C(=O)OCCCCNC[C@H](O)COc1ccccc1
Formula: C29H35N3O8
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: YM-430 is a β1 adrenergic receptor antagonist and a calcium channel antagonist. YM430 could be both an antianginal and antihypertensive agent. YM430 (10(-8)-10(-6) M) inhibited 3, 4-diaminopyridine-induced rhythmic contractions with an IC50 value of 59.2 nM. In anesthetized rats, YM430 (10-100 mg/kg PO) inhibited arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg PO.
Molecular Weight: 553, 612
