Product Overview
YM022 | T17274 | TargetMol Chemicals
CAS: 145084-28-2
Smiles: Cc1cccc(NC(=O)N[C@@H]2N=C(c3ccccc3)c3ccccc3N(CC(=O)c3ccccc3C)C2=O)c1
Formula: C32H28N4O3
Pathway: Immunology/Inflammation|||Microbiology/Virology
Target: CCR
Receptor: N/A
Bioactivity: YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist. YM022 can inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation in vivo. YM022 shows the Ki values of 68 pM and 63 nM for CCK-B and CCK-A receptor, respectively.
Molecular Weight: 516, 601