Product Overview
Zamicastat | T13383 | TargetMol Chemicals
CAS: 1080028-80-3
Smiles: Fc1cc(F)c2OC[C@@H](Cc2c1)n1c(CCNCc2ccccc2)c[nH]c1=S
Formula: C21H21F2N3OS
Pathway: Membrane transporter/Ion channel|||Metabolism|||Neuroscience
Target: BCRP|||Hydroxylase|||P-gp
Receptor: N/A
Bioactivity: Zamicastat is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73.8 μM and 17.0 μM, respectively).
Molecular Weight: 401, 48