Product Overview
ZLD1039 | T29231 | TargetMol Chemicals
CAS: 1826865-46-6
Smiles: CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c3CCCCc3c(C)[nH]c2=O)c1C)-c1ccc(nc1)N1CCN(C)CC1
Formula: C36H48N6O3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: ZLD1039 is a potent, highly selective, and orally bioavailable inhibitor of EZH2. The inhibition of EZH2 methyltransferase activity decreased global histone-3 lysine-27 (H3K27) methylation, and reactivated silenced tumor suppressors connected to increased survival of patients with breast cancer, resulting in the suppression of breast tumor growth and metastasis.
Molecular Weight: 612, 819