Product Overview
Zonisamide | T0267 | TargetMol Chemicals
CAS: 68291-97-4
Smiles: NS(=O)(=O)Cc1noc2ccccc12
Formula: C8H8N2O3S
Pathway: Membrane transporter/Ion channel|||Metabolism
Target: Calcium Channel|||Sodium Channel|||Carbonic Anhydrase
Receptor: N/A
Bioactivity: Zonisamide, a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels results in a reduction of T-type calcium channel currents, or by binding allosterically to GABA receptors. This latter action may lower the uptake of the inhibitory neurotransmitter GABA while increasing the uptake of the excitatory neurotransmitter glutamate.
Molecular Weight: 212, 22
