Product Overview
Zotarolimus | T6033 | TargetMol Chemicals
CAS: 221877-54-9
Smiles: [H][C@@]12CCCCN1C(=O)C(=O)[C@]1(O)O[C@@H](CC[C@H]1C)C[C@H](OC)\C(C)=C\C=C\C=C\[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)\C(C)=C\[C@@H](C)C(=O)C[C@H](OC2=O)[C@H](C)C[C@@H]1CC[C@@H]([C@@H](C1)OC)N1C=NN=N1
Formula: C52H79N5O12
Pathway: PI3K/Akt/mTOR signaling
Target: mTOR
Receptor: N/A
Bioactivity: Zotarolimus, an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).
Molecular Weight: 966, 21
