Product Overview
ZX-29 | T13416 | TargetMol Chemicals
CAS: 2254805-62-2
Smiles: COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCN(C)CC1
Formula: C23H28ClN7O3S
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: ALK
Receptor: N/A
Bioactivity: ZX-29 is a potent and selective inhibitor of ALK(IC50 of 2.1 nM, 1.3 nM and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively), and also induces protective autophagy and has antitumor effect.
Molecular Weight: 518, 03
