Product Overview
1, 5-Isoquinolinediol | T7042 | TargetMol Chemicals
CAS: 5154-02-9
Smiles: Oc1cccc2c(O)nccc12
Formula: C9H7NO2
Pathway: Chromatin/Epigenetic|||DNA Damage/DNA Repair
Target: PARP
Receptor: N/A
Bioactivity: 1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
Molecular Weight: 161, 16
