Product Overview
1-Methyl-2-undecyl-4(1H)-quinolone | TN2553 | TargetMol Chemicals
CAS: 59443-02-6
Smiles: CCCCCCCCCCCc1cc(=O)c2ccccc2n1C
Formula: C21H31NO
Pathway: Metabolism|||Neuroscience
Target: MAO
Receptor: N/A
Bioactivity: 1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.It can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification by inhibiting phosphate cotransporter (PiT-1) gene expression. It also shows moderate antiangiogenic activity against human tumor cells.
Molecular Weight: 313, 5
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