Product Overview
1-Methyl-2-undecyl-4(1H)-quinolone | TN2553 | TargetMol Chemicals
CAS: 59443-02-6
Smiles: CCCCCCCCCCCc1cc(=O)c2ccccc2n1C
Formula: C21H31NO
Pathway: Metabolism|||Neuroscience
Target: MAO
Receptor: N/A
Bioactivity: 1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.It can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification by inhibiting phosphate cotransporter (PiT-1) gene expression. It also shows moderate antiangiogenic activity against human tumor cells.
Molecular Weight: 313, 5
![1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone](https://cdn11.bigcommerce.com/s-2kvb5rm600/images/stencil/500x659/products/52963/49619/TargetMol-768x384__12443.1665998863__58185.1666079859.png?c=1 "1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone")
![6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2, 4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one](https://cdn11.bigcommerce.com/s-2kvb5rm600/images/stencil/500x659/products/47227/43883/TargetMol-768x384__12443.1665998863__07639.1666031580.png?c=1 "6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2, 4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one")
![Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2, 6-dimethyl-](https://cdn11.bigcommerce.com/s-2kvb5rm600/images/stencil/500x659/products/43887/40543/TargetMol-768x384__12443.1665998863__19336.1666026905.png?c=1 "Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2, 6-dimethyl-")
