Product Overview
(±)-10-Hydroxycamptothecin | T1521 | TargetMol Chemicals
CAS: 64439-81-2
Smiles: CCC1(c2c(COC1=O)c(=O)n1Cc3c(c1c2)nc1ccc(cc1c3)O)O
Formula: C20H16N2O5
Pathway: DNA Damage/DNA Repair
Target: Topoisomerase
Receptor: N/A
Bioactivity: (±)-10-Hydroxycamptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Molecular Weight: 364, 35
