Product Overview
2'-Hydroxydaidzein | TN2766 | TargetMol Chemicals
CAS: 7678-85-5
Smiles: Oc1ccc(c(O)c1)-c1coc2cc(O)ccc2c1=O
Formula: C15H10O5
Pathway: Immunology/Inflammation
Target: NADPH-oxidase
Receptor: N/A
Bioactivity: 2'-Hydroxygenistein is an isoflavonoid phytoalexin, it suppresses chemical mediators in inflammatory cells, may have value in treatment and prevention of central and peripheral inflammatory diseases associated with excess production of chemical mediators. 2'-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase and lysozyme from rat neutrophils in response to formyl-Met-Leu-Phe/cytochalasin B (fMLP/CB) with IC(50) values of 2.8+/-0.1 and 5.9+/-1.4 microM, respectively.
Molecular Weight: 270, 24