(2S)-2'-Methoxykurarinone | TN1215

(2S)-2'-Methoxykurarinone | TN1215 | TargetMol Chemicals

CAS: 270249-38-2

Smiles: COc1cc(O)ccc1[C@@H]1CC(=O)c2c(OC)cc(O)c(C[C@@H](CC=C(C)C)C(C)=C)c2O1

Formula: C27H32O6

Pathway: Cytoskeletal Signaling|||Microbiology/Virology|||PI3K/Akt/mTOR signaling

Target: Akt|||Antifection

Receptor: N/A

Bioactivity: (2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells.

Molecular Weight: 452, 54