(2S, 3R, 4S)-4-Hydroxyisoleucine | T2P2919

(2S, 3R, 4S)-4-Hydroxyisoleucine | T2P2919 | TargetMol Chemicals

CAS: 55399-93-4

Smiles: C[C@H](O)[C@H](C)[C@H](N)C(O)=O

Formula: C6H13NO3

Pathway: PI3K/Akt/mTOR signaling

Target: PI3K

Receptor: N/A

Bioactivity: 4-Hydroxyisoleucine (HIL) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secretion from pancreatic cells. HIL activates insulin receptor substrate-associated phosphoinositide 3 (PI3) kinase activity. HIL reduces plasma levels of triglycerides, free fatty acids and cholesterol.

Molecular Weight: 147, 17