Product Overview
7, 8-Didehydrocimigenol | TN3219 | TargetMol Chemicals
CAS: 150972-72-8
Smiles: C[C@@H]1C[C@H]2O[C@]3(O[C@@H]2C(C)(C)O)[C@H](O)[C@@]2(C)C4=CC[C@@H]5[C@]6(CC46CC[C@]2(C)C13)CC[C@H](O)C5(C)C
Formula: C30H46O5
Pathway: Apoptosis|||Cytoskeletal Signaling|||DNA Damage/DNA Repair|||MAPK|||Metabolism|||NF-Κb|||PI3K/Akt/mTOR signaling
Target: ERK|||IκB/IKK|||TNF|||NF-κB|||Akt|||PPAR
Receptor: N/A
Bioactivity: 7, 8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of TNF-α-activated EC which leads to selective inhibition of VCAM-1 expression.
Molecular Weight: 486, 7
