Product Overview
9, 13-Epidioxy-8(14)-abieten-18-oic acid | T5157 | TargetMol Chemicals
CAS: 5309-35-3
Smiles: CC(C)[C@]12CC[C@]3(OO1)C(CC[C@H]1[C@@](C)(CCC[C@]31C)C(O)=O)=C2
Formula: C20H30O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: 9, 13β-Epidioxy-8(14)-abieten-18-oic acid has anti-inflammatory activities, it exhibits moderate activities on NO levels in LPS-stimulated murine microglia BV2 cells, with IC50 values of 57.3 ± 0.2 uM. It is also a potential antitumor-promoting diterpenoid, it shows potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate. 9 α, 13 β -Epidioxyabeit-8(14)en-18-oic acid may contribute to the growth inhibitory effect of the pine needles and may play an important role in the allelopathy of red pine.
Molecular Weight: 334, 5
