Product Overview
A-674563 2HCl(552325-73-2(fb-2hcl)) | T6139L | TargetMol Chemicals
CAS: T6139L
Smiles: Cl.Cl.Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1
Formula: C22H24Cl2N4O
Pathway: Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||MAPK|||PI3K/Akt/mTOR signaling|||Tyrosine Kinase/Adaptors
Target: ERK|||Akt|||PKA|||CDK|||PKC
Receptor: N/A
Bioactivity: A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
Molecular Weight: 431, 36
