Product Overview
A 83-01 | T3031 | TargetMol Chemicals
CAS: 909910-43-6
Smiles: Cc1cccc(n1)-c1nn(cc1-c1ccnc2ccccc12)C(=S)Nc1ccccc1
Formula: C25H19N5S
Pathway: Angiogenesis|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: ALK|||TGF-beta/Smad
Receptor: N/A
Bioactivity: A 83-01 is a selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 with IC50 values of 12 nM, 45 nM and 7.5 nM, respectively.
Molecular Weight: 421, 52
