Acetylcorynoline | T5S2357

(No reviews yet) Write a Review
€410.00 - €623.00
Adding to cart… The item has been added

Product Overview

Acetylcorynoline | T5S2357 | TargetMol Chemicals

CAS: 18797-80-3

Smiles: CN1Cc2c3OCOc3ccc2[C@@]2(C)[C@H](Cc3cc4OCOc4cc3[C@@H]12)OC(C)=O

Formula: C23H23NO6

Pathway: Microbiology/Virology

Target: Antifungal

Receptor: N/A

Bioactivity: 1. Acetylcorynoline has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3. Acetylcorynoline is potential as a possible antiparkinsonian drug. (1) Significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; (2) Prevents α-synuclein aggregation; (3) Restores food-sensing behavior, and dopamine levels; (4) Prolongs life-span in 6-hydroxydopamine-treated N2 strain. 4. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes.

Molecular Weight: 409, 438


(No reviews yet) Write a Review