Product Overview
ADH-1 trifluoroacetate | T1608 | TargetMol Chemicals
CAS: 1135237-88-5
Smiles: OC(=O)C(F)(F)F.CC(C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(N)=O)NC(C)=O
Formula: C24H35F3N8O8S2
Pathway: Metabolism
Target: Dehydrogenase
Receptor: N/A
Bioactivity: Exherin (ADH-1) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis.
Molecular Weight: 684, 71
