Product Overview
Afegostat HCl | T23653 | TargetMol Chemicals
CAS: 161302-93-8
Smiles: Cl.OC[C@H]1CNC[C@@H](O)[C@@H]1O
Formula: C6H14ClNO3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Afegostat is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. Afegostat inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes. Afegostat was an experimental drug for the treatment of certain forms of Gaucher's disease.
Molecular Weight: 183, 63
