[Ala17]-MCH acetate | TP1997L

[Ala17]-MCH acetate | TP1997L | TargetMol Chemicals

CAS: TP1997L

Smiles: O=C1N2[C@](CCC2)([H])C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CCCNC(N)=N)=O)CC3=CC=C(C=C3)O)=O)C(C)C)=O)CCCNC(N)=N)=O)=O)CC(C)C)=O)CCSC)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CCSC)NC([C@H](CC(O)=O)NC([C@@H](NC([C@@H](N)CC(O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O.CC(O)=O

Formula: C99H159N29O28S4

Pathway: GPCR/G Protein

Target: Melanin-concentrating Hormone Receptor (MCHR)

Receptor: N/A

Bioactivity: [Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM(Eu3+ chelate-labeled). [Ala17]-MCH acetate shows selectivity over MCHR2 with Ki of 34 nM.

Molecular Weight: 2331, 76