Product Overview
AMG-337 | T3209 | TargetMol Chemicals
CAS: 1173699-31-4
Smiles: COCCOc1cnc2ccn([C@H](C)c3nnc4c(F)cc(cn34)-c3cnn(C)c3)c(=O)c2c1
Formula: C23H22FN7O3
Pathway: Tyrosine Kinase/Adaptors
Target: c-Met/HGFR
Receptor: N/A
Bioactivity: AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337 inhibits MET kinase activity (IC50: < 5 nM).
Molecular Weight: 463, 473