Product Overview
AMG 837 calcium hydrate | TQ0020 | TargetMol Chemicals
CAS: 1259389-38-2
Smiles: O.[Ca++].CC#CC(CC([O-])=O)c1ccc(OCc2cccc(c2)-c2ccc(cc2)C(F)(F)F)cc1.CC#CC(CC([O-])=O)c1ccc(OCc2cccc(c2)-c2ccc(cc2)C(F)(F)F)cc1
Formula: C52H42CaF6O7
Pathway: Endocrinology/Hormones|||GPCR/G Protein
Target: GPR
Receptor: N/A
Bioactivity: AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 > 10, 000 nM).
Molecular Weight: 932, 969
