Product Overview
Anatabine | TN3410 | TargetMol Chemicals
CAS: 581-49-7
Smiles: C1N[C@@H](CC=C1)c1cccnc1
Formula: C10H12N2
Pathway: Apoptosis|||Immunology/Inflammation|||JAK/STAT signaling|||Neuroscience|||NF-Κb|||Stem Cells
Target: Beta Amyloid|||IL Receptor|||TNF|||NF-κB|||BACE|||COX|||STAT
Receptor: N/A
Bioactivity: Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheimer's disease effects, it inhibits BACE-1 transcription and reduces BACE-1 protein levels in human neuronal like SHSY-5Y cells suggesting that the Aβ lowering properties of anatabine are mediated via a regulation of BACE-1 expression.
Molecular Weight: 160, 22
