Product Overview
Angoline | TN6739 | TargetMol Chemicals
CAS: 21080-31-9
Smiles: CN(C1OC)c2c(cc3OCOc3c3)c3ccc2-c(cc2)c1c(OC)c2OC
Formula: C22H21NO5
Pathway: Immunology/Inflammation|||JAK/STAT signaling|||Stem Cells
Target: IL Receptor|||STAT
Receptor: N/A
Bioactivity: Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.
Molecular Weight: 379, 41