Apelin-36(human) | TP2093

Apelin-36(human) | TP2093 | TargetMol Chemicals

CAS: 252642-12-9

Smiles:

Formula: C184H297N69O43S

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.

Molecular Weight: 4195, 87