Apelin-36(rat, mouse) | TP2094

Apelin-36(rat, mouse) | TP2094 | TargetMol Chemicals

CAS: 230299-95-3

Smiles:

Formula: C185H304N68O43S

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: Endogenous APJ receptor agonist that is secreted by adipocytes. Binds with high affinity to APJ receptors (IC50 = 5.4 nM) and potently inhibits cAMP production in vitro (EC50 = 0.52 nM). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.

Molecular Weight: 4200, 93