Product Overview
Aplidine | T9715 | TargetMol Chemicals
CAS: 137219-37-5
Smiles: CC[C@@H]([C@@H]1[C@@H](O)CC(O[C@@H](C(C)C)C([C@H](C)C(N[C@@H](CC(C)C)C(N2CCC[C@H]2C(N(C)[C@@H](CC3=CC=C(OC)C=C3)C(O[C@H](C)[C@H](NC([C@H](N(C([C@@H]4CCCN4C(C(C)=O)=O)=O)C)CC(C)C)=O)C(N1)=O)=O)=O)=O)=O)=O)=O)C
Formula: C57H87N7O15
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology
Target: SARS-CoV|||DNA/RNA Synthesis
Receptor: N/A
Bioactivity: Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM).
Molecular Weight: 1110, 34