Product Overview
(+)-Apogossypol | T13459 | TargetMol Chemicals
CAS: 66389-74-0
Smiles: OC1=C2C=C(O)C(O)=C(C(C)C)C2=CC(C)=[C@]1[C@]3=C(C)C=C4C(C(C)C)=C(O)C(O)=CC4=C3O.[S]
Formula: C28H30O6S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: (+)-Apogossypol is an antagonist of pan-BCL-2. (+)-Apogossypol binds to Mcl-1(Bcl-2 and Bcl-xL with EC50s of 2.6, 2.8 and 3.69 μM, respectively).
Molecular Weight: 494, 6