Ardisiacrispin A | T3S2325

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Ardisiacrispin A | T3S2325 | TargetMol Chemicals

CAS: 23643-61-0

Smiles: [H][C@@]1(O[C@@H]2[C@H]([C@@H]([C@H](O[C@]2(O[C@H]3CO[C@@](O[C@@H]4C(C)([C@@]([H])([C@@]5(CC4)C)CC[C@@]6(C)[C@@](C)([C@@]7(CC[C@@]65[H])OC8)C[C@H]([C@]98[C@]7(C[C@@](C=O)(CC9)C)[H])O)C)([C@@H]([C@@H]3O)O[C@@]%10([H])[C@@H]([C@H]([C@@H]([C@H](O%10)CO)O)O)O)[H])[H])CO)O)O)OC[C@H]([C@@H]([C@H]1O)O)O

Formula: C52H84O22

Pathway: Microbiology/Virology

Target: HSV

Receptor: N/A

Bioactivity: Ardisiacrispin A has cytotoxic activity toward HepG2 cancer cell with the GI(50) value of 1.56μM, it could inhibit the proliferation of Bel-7402 cells by inducing apoptosis and disassembling microtubule.Ardisiacrispin(A+B) exhibit prominent abilities to inhibit the proliferation of HL-60 cells by blocking the cell cycle at S phase and inducing apoptosis.

Molecular Weight: 1061, 22

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