Product Overview
Aristolactam I | T3S1227 | TargetMol Chemicals
CAS: 13395-02-3
Smiles: COc1cccc2c1cc1NC(=O)c3cc4OCOc4c2c13
Formula: C17H11NO4
Pathway: Apoptosis|||Proteases/Proteasome
Target: Apoptosis|||Caspase
Receptor: N/A
Bioactivity: 1. Aristololactam I has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF-beta1 pathway. 3. Aristololactam I may be one of toxic metabolites in Chinese herbs containing AA which participate in renal damage and fibrosis.
Molecular Weight: 293, 278
