Product Overview
AST 487 | T4053 | TargetMol Chemicals
CAS: 630124-46-8
Smiles: CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1
Formula: C26H30F3N7O2
Pathway: Angiogenesis|||Apoptosis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: VEGFR|||FLT|||c-RET|||Bcr-Abl|||c-Kit
Receptor: N/A
Bioactivity: AST 487 is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.
Molecular Weight: 529, 568
