Product Overview
AVN-944 | T1979 | TargetMol Chemicals
CAS: 297730-17-7
Smiles: c1(ocnc1)c1c(cc(cc1)NC(=O)Nc1cc(ccc1)[C@@H](NC(=O)O[C@@H](CC#N)CC)C)OC
Formula: C25H27N5O5
Pathway: Metabolism
Target: Dehydrogenase
Receptor: N/A
Bioactivity: AVN-944(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
Molecular Weight: 477, 51