Product Overview
AZ32 | T4443 | TargetMol Chemicals
CAS: 2288709-96-4
Smiles: CNC(=O)c1ccc(cc1)c2cnc3cnc(cn23)c4ccccc4
Formula: C20H16N4O
Pathway: DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Target: ATM/ATR
Receptor: N/A
Bioactivity: AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.
Molecular Weight: 328, 37