azd1390 | T5175

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€224.00 - €1,284.00
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TMC-T5175
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Product Overview

azd1390 | T5175 | TargetMol Chemicals

CAS: 2089288-03-7

Smiles: CC(C)n1c2c(cnc3cc(F)c(cc23)-c2ccc(OCCCN3CCCCC3)nc2)n(C)c1=O

Formula: C27H32FN5O2

Pathway: DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling

Target: ATM/ATR

Receptor: N/A

Bioactivity: AZD1390 is an exceptionally potent inhibitor of ATM in cells (IC50: 0.78 nM) with >10, 000-fold selectivity over closely related members of the PIKK family of enzymes.

Molecular Weight: 477, 584

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