Product Overview
azd1390 | T5175 | TargetMol Chemicals
CAS: 2089288-03-7
Smiles: CC(C)n1c2c(cnc3cc(F)c(cc23)-c2ccc(OCCCN3CCCCC3)nc2)n(C)c1=O
Formula: C27H32FN5O2
Pathway: DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Target: ATM/ATR
Receptor: N/A
Bioactivity: AZD1390 is an exceptionally potent inhibitor of ATM in cells (IC50: 0.78 nM) with >10, 000-fold selectivity over closely related members of the PIKK family of enzymes.
Molecular Weight: 477, 584
