Product Overview
Balixafortide | TP2141L | TargetMol Chemicals
CAS: 1051366-32-5
Smiles:
Formula: C80H112N22O21S2
Pathway: Autophagy|||GPCR/G Protein|||Immunology/Inflammation
Target: CXCR
Receptor: N/A
Bioactivity: Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM and it is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects[1][2]. Balixafortide blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7.
Molecular Weight: 1782, 03
