Balsalazide sodium hydrate | T4615

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Product Overview

Balsalazide sodium hydrate | T4615 | TargetMol Chemicals

CAS: 150399-21-6

Smiles: O.O.[Na+].[Na+].Oc1ccc(cc1C([O-])=O)\N=N\c1ccc(cc1)C(=O)NCCC([O-])=O

Formula: C17H17N3Na2O8

Pathway: Immunology/Inflammation|||JAK/STAT signaling|||Stem Cells

Target: STAT|||Interleukin

Receptor: N/A

Bioactivity: Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug. High dose balsalazide (3.0 g twice daily) was superior in maintaining remission in patients with ulcerative colitis compared with a low dose (1.5 g twice daily) or a standard dose of mesalazine (0.5 g three times daily). All three treatments were safe and well tolerated [1]. Balsalazide is approved for the treatment of mild-to-moderate active UC. It is efficacious for the induction of remission in mild to moderate UC and has a favorable safety profile, with the added advantages of greater efficacy of remission induction and rapidity of onset [2].

Molecular Weight: 437, 316


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