Product Overview
BI-1347 | T5405 | TargetMol Chemicals
CAS: 2163056-91-3
Smiles: CN(C)C(=O)Cn1cc(cn1)-c1ccc(cc1)-c1cncc2ccccc12
Formula: C22H20N4O
Pathway: Cell Cycle/Checkpoint
Target: CDK
Receptor: N/A
Bioactivity: BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.
Molecular Weight: 356, 429
