Product Overview
BIPM | T26821 | TargetMol Chemicals
CAS: 1070424-33-7
Smiles: O=C(C1CCCN(Cc2cccc3cnccc23)C1)c1ccc2OCOc2c1
Formula: C23H22N2O3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: BIPM is a potent inhibitor of Rho-associated protein kinase 2 (ROCK2). Exposure of SH-SY5Y cells to BIPM led to significant changes in cell migration, actin stress fibers and neurite length. BIPM significantly inhibits phosphorylation of cofilin, a regulatory protein of actin cytoskeleton.
Molecular Weight: 374, 44